Thiopurine metabolite measurement - not for everyone

Thiopurine metabolite measurement - not for everyone.

Microrefugia: Not for everyone

Microrefugia are sites that support populations of species when their ranges contract during unfavorable climate episodes. Here, we review and discuss two aspects relevant for microrefugia. First, distributions of different species are influenced by different climatic variables. Second, climatic variables differ in the degree of local decoupling from the regional climate. Based on this, we sugg...

Pair Programming: Not for Everyone?

Developments in CS1 pedagogy seek to improve the capabilities of students in their understanding of how to write programs. This involves learning how to solve various types of problems through a systematic approach, a challenging task for most students. “Pair programming” as a pedagogical approach, is one in which students help one another learn how to program by working in pairs on programming...

Transesophageal echocardiography: not for everyone?

Transesophageal Echocardiography: Not for Everyone? To the Editor: We read with interest the article by de Bruijn et al comparing transesophageal and transthoracic echocardiography (TEE versus TEE) for the evaluation of TIA or stroke.1 We congratulate the investigators on this important study. TEE proved superior to TTE for identification of a cardiac embolic source in patients with TIA or stro...

Role of thiopurine metabolite testing and thiopurine methyltransferase determination in pediatric IBD.

Thiopurines have been used in inflammatory bowel disease (IBD) for >30 years, and measurements of both thiopurine methyltransferase (TPMT) and thiopurine (TP) metabolites, 6-thioguanine nucleotides (6-TGN) and 6-methylmercaptopurine (6-MMP), have been readily available. The North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition (NASPGHAN) Committee on Inflammatory Bowe...